- Biomass Valorization and production of proteins in eukaryotes >> Presentation

Biomass Valorization and production of proteins in eukaryotes >> Presentation

We focus on three major objectives:

Production, biochemical and molecular studies, improvement of the performance of fungal enzymes to apply them in the valorisation of biomass in all its forms and in the improvement of industrial processes.
Expression of proteins of biotechnology and medical interest in bacteria, yeasts and fungi mainly to produce molecules with high added value.
Functional analysis of genes involved in human diseases including cancer.

Specific research objectives (as they appear in our research contract with our ministery of research):

Production, biochemical and molecular studies of enzymes: cellulases, hemicellulases (xylanases also say), pectinases, proteases, xylose reductase, lipase and tyrosinase.
Application of enzymes in various processes of biomass from plant, marine and animal origins.
Production, biochemical and molecular studies of the AFP (Anti Fungal Peptide) and its applications in plants and animals protection.
Development of efficient expression system in fungi, such as: Operating system fungal (in particular the constitutive mutant CT1) in the expression of proteins of interest.
Production of useful proteins in a heterologous context (mainly bacteria and yeast: Examples: enzymes mentioned above, the envelope proteins of hepatitis B, the tumor suppressor p53, the oncoprotein LMP1, thioredoxin and other proteins of biotechnological interest.
Production of antibodies, diagnostic kits and peptide antagonists.
Molecular studies and functional analysis of human genes involved in human diseases including cancer…